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Incidence of new diabetes following CABG surgery: Analysis of a single centre registry data

BACKGROUND: About 40–50% of patients undergoing coronary artery bypass graft (CABG) surgery have diabetes. The prevalence of impaired glucose tolerance (IGT) is also high in this group, however, incidence of new diabetes following CABG surgery is unknown. Objectives: To determine incidence of new di...

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Autores principales: Lodha, Sailesh, Sharma, krishna Kumar, Bana, Ajeet, Mehta, Navneet, Gupta, Rajeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310740/
https://www.ncbi.nlm.nih.gov/pubmed/30595262
http://dx.doi.org/10.1016/j.ihj.2018.11.017
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author Lodha, Sailesh
Sharma, krishna Kumar
Bana, Ajeet
Mehta, Navneet
Gupta, Rajeev
author_facet Lodha, Sailesh
Sharma, krishna Kumar
Bana, Ajeet
Mehta, Navneet
Gupta, Rajeev
author_sort Lodha, Sailesh
collection PubMed
description BACKGROUND: About 40–50% of patients undergoing coronary artery bypass graft (CABG) surgery have diabetes. The prevalence of impaired glucose tolerance (IGT) is also high in this group, however, incidence of new diabetes following CABG surgery is unknown. Objectives: To determine incidence of new diabetes and the impact on ICU and hospital stay in patients undergoing CABG surgery in India, we performed a registry-based study. METHODS: Prospectively collected data among consecutive adult cardiac surgical patients who underwent CABG surgery at a single hospital were analyzed. Descriptive statistics are reported. RESULTS: We recruited 1559 consecutive patients (men 1355, women 204) and analyzed data among 933 non-diabetic patients. Patients with known diabetes (n = 626, 40%) were excluded. 57 (6.1%) of the 933 non-diabetic patients developed persistently high glucose levels at discharge with incidence rate of 61 + 5/1000. Patients who developed diabetes had similar age and body mass index vs those who did not, but had greater preoperative IGT (44.6 vs 13.7%) and more time-period in intensive care unit (102.0 + 75 vs 80.2 + 29 hours) as well as in hospital (11.7 + 5.7 vs 9.6 + 2.4 days) (p < 0.001). CONCLUSION: In a significant proportion of non-diabetic patients diabetes is unmasked after CABG. This is more likely in those with impaired glucose tolerance and prolonged period in intensive care and hospital.
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spelling pubmed-63107402019-12-01 Incidence of new diabetes following CABG surgery: Analysis of a single centre registry data Lodha, Sailesh Sharma, krishna Kumar Bana, Ajeet Mehta, Navneet Gupta, Rajeev Indian Heart J Clinical and Preventive Cardiology BACKGROUND: About 40–50% of patients undergoing coronary artery bypass graft (CABG) surgery have diabetes. The prevalence of impaired glucose tolerance (IGT) is also high in this group, however, incidence of new diabetes following CABG surgery is unknown. Objectives: To determine incidence of new diabetes and the impact on ICU and hospital stay in patients undergoing CABG surgery in India, we performed a registry-based study. METHODS: Prospectively collected data among consecutive adult cardiac surgical patients who underwent CABG surgery at a single hospital were analyzed. Descriptive statistics are reported. RESULTS: We recruited 1559 consecutive patients (men 1355, women 204) and analyzed data among 933 non-diabetic patients. Patients with known diabetes (n = 626, 40%) were excluded. 57 (6.1%) of the 933 non-diabetic patients developed persistently high glucose levels at discharge with incidence rate of 61 + 5/1000. Patients who developed diabetes had similar age and body mass index vs those who did not, but had greater preoperative IGT (44.6 vs 13.7%) and more time-period in intensive care unit (102.0 + 75 vs 80.2 + 29 hours) as well as in hospital (11.7 + 5.7 vs 9.6 + 2.4 days) (p < 0.001). CONCLUSION: In a significant proportion of non-diabetic patients diabetes is unmasked after CABG. This is more likely in those with impaired glucose tolerance and prolonged period in intensive care and hospital. Elsevier 2018-12 2018-12-07 /pmc/articles/PMC6310740/ /pubmed/30595262 http://dx.doi.org/10.1016/j.ihj.2018.11.017 Text en © 2018 Cardiological Society of India. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Clinical and Preventive Cardiology
Lodha, Sailesh
Sharma, krishna Kumar
Bana, Ajeet
Mehta, Navneet
Gupta, Rajeev
Incidence of new diabetes following CABG surgery: Analysis of a single centre registry data
title Incidence of new diabetes following CABG surgery: Analysis of a single centre registry data
title_full Incidence of new diabetes following CABG surgery: Analysis of a single centre registry data
title_fullStr Incidence of new diabetes following CABG surgery: Analysis of a single centre registry data
title_full_unstemmed Incidence of new diabetes following CABG surgery: Analysis of a single centre registry data
title_short Incidence of new diabetes following CABG surgery: Analysis of a single centre registry data
title_sort incidence of new diabetes following cabg surgery: analysis of a single centre registry data
topic Clinical and Preventive Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310740/
https://www.ncbi.nlm.nih.gov/pubmed/30595262
http://dx.doi.org/10.1016/j.ihj.2018.11.017
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