Virus-inclusive single-cell RNA sequencing reveals the molecular signature of progression to severe dengue

Dengue virus (DENV) infection can result in severe complications. However, the understanding of the molecular correlates of severity is limited, partly due to difficulties in defining the peripheral blood mononuclear cells (PBMCs) that contain DENV RNA in vivo. Accordingly, there are currently no bi...

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Detalles Bibliográficos
Autores principales: Zanini, Fabio, Robinson, Makeda L., Croote, Derek, Sahoo, Malaya Kumar, Sanz, Ana Maria, Ortiz-Lasso, Eliana, Albornoz, Ludwig Luis, Rosso, Fernando, Montoya, Jose G., Goo, Leslie, Pinsky, Benjamin A., Quake, Stephen R., Einav, Shirit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310786/
https://www.ncbi.nlm.nih.gov/pubmed/30530648
http://dx.doi.org/10.1073/pnas.1813819115

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