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Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks
Either expression level or transcriptional activity of various nuclear receptors (NRs) have been demonstrated to be under circadian control. With a few exceptions, little is known about the roles of NRs as direct regulators of the circadian circuitry. Here we show that the nuclear receptor HNF4A str...
Autores principales: | Qu, Meng, Duffy, Tomas, Hirota, Tsuyoshi, Kay, Steve A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310821/ https://www.ncbi.nlm.nih.gov/pubmed/30530698 http://dx.doi.org/10.1073/pnas.1816411115 |
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