Characterization of interaction and ubiquitination of phosphoenolpyruvate carboxykinase by E3 ligase UBR5

Phosphoenolpyruvate carboxykinase (PEPCK1) is ubiquitinated by E3 ubiquitin ligase UBR5, which was thought to be facilitated by the acetylation of Lys70, Lys71 and Lys594 in PEPCK1. Here, we made a series of UBR5 HECT domain truncation variants and, through pull-down assay, showed that the N-termina...

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Detalles Bibliográficos
Autores principales: Shen, Qingya, Qiu, Zhiyu, Wu, Wenping, Zheng, Jimin, Jia, Zongchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310884/
https://www.ncbi.nlm.nih.gov/pubmed/30552140
http://dx.doi.org/10.1242/bio.037366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310884/
https://www.ncbi.nlm.nih.gov/pubmed/30552140
http://dx.doi.org/10.1242/bio.037366

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