Cargando…

A genome wide SNP genotyping study in the Tunisian population: specific reporting on a subset of common breast cancer risk loci

BACKGROUND: Breast cancer is the most common cancer in women worldwide. Around 50% of breast cancer familial risk has been so far explained by known susceptibility alleles with variable levels of risk and prevalence. The vast majority of these breast cancer associated variations reported to date are...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hamdi, Yosr, Ben Rekaya, Mariem, Jingxuan, Shan, Nagara, Majdi, Messaoud, Olfa, Benammar Elgaaied, Amel, Mrad, Ridha, Chouchane, Lotfi, Boubaker, Mohamed Samir, Abdelhak, Sonia, Boussen, Hamouda, Romdhane, Lilia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310952/ https://www.ncbi.nlm.nih.gov/pubmed/30594178 http://dx.doi.org/10.1186/s12885-018-5133-8

Ejemplares similares

Family specific genetic predisposition to breast cancer: results from Tunisian whole exome sequenced breast cancer cases
por: Hamdi, Yosr, et al.
Publicado: (2018)

Health influenced by genetics: A first comprehensive analysis of breast cancer high and moderate penetrance susceptibility genes in the Tunisian population
por: Boujemaa, Maroua, et al.
Publicado: (2022)

Identification of Novel BRCA1 and RAD50 Mutations Associated With Breast Cancer Predisposition in Tunisian Patients
por: Mighri, Najah, et al.
Publicado: (2020)

A map of copy number variations in the Tunisian population: a valuable tool for medical genomics in North Africa
por: Romdhane, Lilia, et al.
Publicado: (2021)

Further Evidence of Mutational Heterogeneity of the XPC Gene in Tunisian Families: A Spectrum of Private and Ethnic Specific Mutations
por: Ben Rekaya, Mariem, et al.
Publicado: (2013)

Spectrum of Genetic Diseases in Tunisia: Current Situation and Main Milestones Achieved
por: Mezzi, Nessrine, et al.
Publicado: (2021)

Identification of Eleven Novel BRCA Mutations in Tunisia: Impact on the Clinical Management of BRCA Related Cancers
por: Hamdi, Yosr, et al.
Publicado: (2021)

Association between epidemiological and clinico-pathological features of breast cancer with prognosis, family history, Ki-67 proliferation index and survival in Tunisian breast cancer patients
por: Mighri, Najah, et al.
Publicado: (2022)

A Founder Large Deletion Mutation in Xeroderma Pigmentosum-Variant Form in Tunisia: Implication for Molecular Diagnosis and Therapy
por: Ben Rekaya, Mariem, et al.
Publicado: (2014)

Germline copy number variations in BRCA1/2 negative families: Role in the molecular etiology of hereditary breast cancer in Tunisia
por: Boujemaa, Maroua, et al.
Publicado: (2021)

Identification of a ERCC5 c.2333T>C (L778P) Variant in Two Tunisian Siblings With Mild Xeroderma Pigmentosum Phenotype
por: Chikhaoui, Asma, et al.
Publicado: (2019)

miRNAs in Sera of Tunisian patients discriminate between inflammatory breast cancer and non-inflammatory breast cancer
por: Hamdi, Khouloud, et al.
Publicado: (2014)

Coexistence of mal de Meleda and congenital cataract in a consanguineous Tunisian family: two case reports
por: Bchetnia, Mbarka, et al.
Publicado: (2010)

Pharmacogenetic landscape of Metabolic Syndrome components drug response in Tunisia and comparison with worldwide populations
por: Jmel, Haifa, et al.
Publicado: (2018)

Hereditary breast cancer in Middle Eastern and North African (MENA) populations: identification of novel, recurrent and founder BRCA1 mutations in the Tunisian population
por: Mahfoudh, Wijden, et al.
Publicado: (2011)

CD99 and HLA-II Immunostaining in Breast Cancer Tissue and Their Correlation with Lymph Node Metastasis
por: Baccar, Amal, et al.
Publicado: (2013)

The Developing Country Reactions to Biomedical Techniques and Plant Biotechnology: The Tunisian Experience
por: Tebourski, Fethi, et al.
Publicado: (2004)

A new locus on chromosome 22q13.31 linked to recessive genetic epilepsy with febrile seizures plus (GEFS+) in a Tunisian consanguineous family
por: Belhedi, Nejla, et al.
Publicado: (2013)

First genetic characterization of Xeroderma pigmentosum in Libya: High frequency of XP‐C founder mutation
por: Khalat, Najlaa, et al.
Publicado: (2023)

Alpha-mannosidosis in Tunisian consanguineous families: Potential involvement of variants in GHR and SLC19A3 genes in the variable expressivity of cognitive impairment
por: Mkaouar, Rahma, et al.
Publicado: (2021)

High frequency of exon 15 deletion in the FANCA gene in Tunisian patients affected with Fanconi anemia disease: implication for diagnosis
por: Amouri, Ahlem, et al.
Publicado: (2014)

Impact of Metabolism on T-Cell Differentiation and Function and Cross Talk with Tumor Microenvironment
por: Kouidhi, Soumaya, et al.
Publicado: (2017)

Case Report: Identification of Novel Variants in ERCC4 and DDB2 Genes in Two Tunisian Patients With Atypical Xeroderma Pigmentosum Phenotype
por: Nabouli, Imen, et al.
Publicado: (2021)

Genome-Wide Association Studies (GWAS) breast cancer susceptibility loci in Arabs: susceptibility and prognostic implications in Tunisians
por: Shan, Jingxuan, et al.
Publicado: (2012)

Targeting Tumor Metabolism: A New Challenge to Improve Immunotherapy
por: Kouidhi, Soumaya, et al.
Publicado: (2018)

Brain metastases epidemiology in a Tunisian population: trends and outcome
por: Benna, Mehdi, et al.
Publicado: (2018)

Influence of socioeconomic lifestyle factors and genetic polymorphism on type 2 diabetes occurrences among Tunisian Arab and Berber groups of Djerba Island
por: Ouederni, Thouraya Baroudi, et al.
Publicado: (2009)

Deep analysis of the LRTOMTc.242G>A variant in non‐syndromic hearing loss North African patients and the Berber population: Implications for genetic diagnosis and genealogical studies
por: Mosrati, Mohamed Ali, et al.
Publicado: (2021)

Factor VIII haplotypes frequencies in Tunisian hemophiliacs A
por: Elmahmoudi, Hejer, et al.
Publicado: (2011)

Identification of BRCA2 Cis Double Heterozygous Breast Cancer Cases Using Whole Exome Sequencing: Phenotypic Expression and Impact on Personalized Oncology
por: Hamdi, Yosr, et al.
Publicado: (2021)

Aurora a Overexpression and pVHL Reduced Expression Are Correlated with a Bad Kidney Cancer Prognosis
por: Ferchichi, Imen, et al.
Publicado: (2012)

Cystic fibrosis in Tunisian children: a review of 32 children
por: Boussetta, Khedija, et al.
Publicado: (2018)

Understanding COVID-19 vaccine hesitancy and resistance: another challenge in cancer patients
por: Mejri, Nesrine, et al.
Publicado: (2021)

Poliomyelitis alert on Tunisian borders: response and challenges
por: Ben Mrad, I, et al.
Publicado: (2023)

PIK3CA mutations in breast cancer: A Tunisian series
por: Ben Rekaya, Mariem, et al.
Publicado: (2023)

Tolllike receptor 4 (TLR4) polymorphisms in Tunisian patients with Crohn's disease: genotype-phenotype correlation
por: Zouiten-Mekki, Lilia, et al.
Publicado: (2009)

Identification of novel pathogenic MSH2 mutation and new DNA repair genes variants: investigation of a Tunisian Lynch syndrome family with discordant twins
por: Jaballah-Gabteni, Amira, et al.
Publicado: (2019)

Intrinsic and Tumor Microenvironment-Induced Metabolism Adaptations of T Cells and Impact on Their Differentiation and Function
por: Kouidhi, Soumaya, et al.
Publicado: (2016)

Willingness to participate in health research: Tunisian survey
por: Bouida, Wahid, et al.
Publicado: (2016)

Association of LRP5 genotypes with osteoporosis in Tunisian post-menopausal women
por: Sassi, Rim, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_vff8edonhh0ula4ovt7lm013ig