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Shikonin sensitizes A549 cells to TRAIL-induced apoptosis through the JNK, STAT3 and AKT pathways

BACKGROUND: TRAIL, tumor necrosis factor-related apoptosis-inducing ligand, can selectively kill cancer cells with little or no cytotoxicity toward normal human cells and is regarded as a potential relatively safe antitumor drug. However, some cancer cells are resistant to TRAIL-induced apoptosis. T...

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Detalles Bibliográficos
Autores principales:	Guo, Zhi Lan, Li, Jing Zhe, Ma, Yan Yan, Qian, Dan, Zhong, Ju Ying, Jin, Meng Meng, Huang, Peng, Che, Lu Yang, Pan, Bing, Wang, Yi, Sun, Zhen Xiao, Liu, Chang Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310954/ https://www.ncbi.nlm.nih.gov/pubmed/30594131 http://dx.doi.org/10.1186/s12860-018-0179-7

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