Cerebrospinal fluid penetration of very high-dose meropenem: a case report

BACKGROUND: Standard dosing of meropenem (2 g t.i.d.) produces CSF concentrations of only 1–2 mg/L which is inferior to the clinical breakpoint for most Gram-negative bacteria. There is therefore concern that dosing must be increased in order to achieve therapeutic CSF concentrations for bacteria wi...

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Detalles Bibliográficos
Autores principales: Kerz, Thomas, von Loewenich, Friederike D., Roberts, Jason, Neulen, Axel, Ringel, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310956/
https://www.ncbi.nlm.nih.gov/pubmed/30594199
http://dx.doi.org/10.1186/s12941-018-0299-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310956/
https://www.ncbi.nlm.nih.gov/pubmed/30594199
http://dx.doi.org/10.1186/s12941-018-0299-0

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