Cargando…
Cerebrospinal fluid penetration of very high-dose meropenem: a case report
BACKGROUND: Standard dosing of meropenem (2 g t.i.d.) produces CSF concentrations of only 1–2 mg/L which is inferior to the clinical breakpoint for most Gram-negative bacteria. There is therefore concern that dosing must be increased in order to achieve therapeutic CSF concentrations for bacteria wi...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310956/ https://www.ncbi.nlm.nih.gov/pubmed/30594199 http://dx.doi.org/10.1186/s12941-018-0299-0 |