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Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration

BACKGROUND: Neuronal cell loss contributes to the pathology of acute and chronic neurodegenerative diseases, including Alzheimer’s disease (AD). It remains crucial to identify molecular mechanisms sensitizing neurons to various insults and cell death. To date, the multifunctional, autophagy-related...

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Detalles Bibliográficos
Autores principales:	Bieri, Gregor, Lucin, Kurt M., O’Brien, Caitlin E., Zhang, Hui, Villeda, Saul A., Wyss-Coray, Tony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310967/ https://www.ncbi.nlm.nih.gov/pubmed/30594228 http://dx.doi.org/10.1186/s13024-018-0302-4

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