Downregulation of TGF-β1 suppressed proliferation and increased chemosensitivity of ovarian cancer cells by promoting BRCA1/Smad3 signaling

BACKGROUND: Studies have demonstrated that transforming growth factor beta-1 (TGF-β1) exhibits oncogenic activity in different types of cancer, including ovarian cancer (OC). However, its regulatory mechanism in OC and whether TGF-β1 is involved in chemosensitivity regulation remains unclear. Thus,...

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Detalles Bibliográficos
Autores principales: Wang, Yanqiu, Xiang, Jun, Wang, Jianjun, Ji, Yazhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310971/
https://www.ncbi.nlm.nih.gov/pubmed/30594239
http://dx.doi.org/10.1186/s40659-018-0205-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310971/
https://www.ncbi.nlm.nih.gov/pubmed/30594239
http://dx.doi.org/10.1186/s40659-018-0205-4

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