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Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation

BACKGROUND: Altered mitochondrial function and large-scale changes to DNA methylation patterns in the nuclear genome are both hallmarks of colorectal cancer (CRC). Mitochondria have multiple copies of a 16 kb circular genome that contains genes that are vital for their function. While DNA methylatio...

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Detalles Bibliográficos
Autores principales:	Morris, M. J., Hesson, L. B., Poulos, R. C., Ward, R. L., Wong, J. W. H., Youngson, N. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311003/ https://www.ncbi.nlm.nih.gov/pubmed/30619609 http://dx.doi.org/10.1186/s40364-018-0151-x

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