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Tophus resolution in patients with chronic refractory gout who have persistent urate-lowering responses to pegloticase

BACKGROUND: Pegloticase is a recombinant mammalian uricase conjugated to polyethylene glycol approved in the United States for treatment of chronic refractory gout. It can profoundly decrease serum urate to < 1 mg/dl. In patients receiving pegloticase who did not generate high-titer antidrug anti...

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Detalles Bibliográficos
Autores principales:	Mandell, Brian F., Yeo, Anthony E., Lipsky, Peter E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311031/ https://www.ncbi.nlm.nih.gov/pubmed/30594229 http://dx.doi.org/10.1186/s13075-018-1782-x

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