Gancao (Glycyrrhizae Radix) provides the main contribution to Shaoyao-Gancao decoction on enhancements of CYP3A4 and MDR1 expression via pregnane X receptor pathway in vitro

BACKGROUND: Chinese herbal formula Shaoyao Gancao decoction (SGD) is often used as an adjuvant with chemotherapeutic agents to treat cancer. Due to the herb-drug interactions, the alternations of drug metabolic enzyme and drug transporters induced by SGD deserve to be explored. We aimed to investiga...

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Detalles Bibliográficos
Autores principales: Feng, Dandan, Tang, Tao, Fan, Rong, Luo, Jiekun, Cui, Hanjin, Wang, Yang, Gan, Pingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311034/
https://www.ncbi.nlm.nih.gov/pubmed/30594244
http://dx.doi.org/10.1186/s12906-018-2402-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311034/
https://www.ncbi.nlm.nih.gov/pubmed/30594244
http://dx.doi.org/10.1186/s12906-018-2402-7

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