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Distal regulatory elements identified by methylation and hydroxymethylation haplotype blocks from mouse brain
BACKGROUND: 5-Hydroxymethylcytosine (5hmC) is an oxidation product of 5-methylcytosine (5mC), and adjacent CpG sites in mammalian genome can be co-methylated and co-hydroxymethylated due to the processivity of DNMT and TET enzymes. RESULTS: We applied TAB-seq and oxBS-seq to selectively detect 5hmC...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311040/ https://www.ncbi.nlm.nih.gov/pubmed/30594220 http://dx.doi.org/10.1186/s13072-018-0248-3 |