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Investigating the mechanism by which SMAD3 induces PAX6 transcription to promote the development of non-small cell lung cancer

BACKGROUND: This study investigated the function of SMAD3 (SMAD family member 3) in regulating PAX6 (paired box 6) in non-small cell lung cancer. METHODS: First, qRT-PCR was employed to detect SMAD3 expression in cancer tissues along with normal tissues and four cell lines, including BEAS-2B, H125,...

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Detalles Bibliográficos
Autores principales: Qian, Zhe, Zhang, Qiankun, Hu, Ying, Zhang, Tongmei, Li, Jie, Liu, Zan, Zheng, Hua, Gao, Yuan, Jia, Wenyun, Hu, Aimin, Li, Baolan, Hao, Jiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311080/
https://www.ncbi.nlm.nih.gov/pubmed/30594196
http://dx.doi.org/10.1186/s12931-018-0948-z