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Assessment and management of fluid overload in children on dialysis
Dysregulation of intravascular fluid leads to chronic volume overload in children with end-stage kidney disease (ESKD). Sequelae include left ventricular hypertrophy and remodeling and impaired cardiac function. As a result, cardiovascular complications are the commonest cause of mortality in the pe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311194/ https://www.ncbi.nlm.nih.gov/pubmed/29523958 http://dx.doi.org/10.1007/s00467-018-3916-4 |
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author | Hayes, Wesley Paglialonga, Fabio |
author_facet | Hayes, Wesley Paglialonga, Fabio |
author_sort | Hayes, Wesley |
collection | PubMed |
description | Dysregulation of intravascular fluid leads to chronic volume overload in children with end-stage kidney disease (ESKD). Sequelae include left ventricular hypertrophy and remodeling and impaired cardiac function. As a result, cardiovascular complications are the commonest cause of mortality in the pediatric dialysis population. The clinical need to optimize intravascular volume in children with ESKD is clear; however, its assessment and management is the most challenging aspect of the pediatric dialysis prescription. Minimizing chronic fluid overload is a key priority; however, excessive ultrafiltration is toxic to the myocardium and can precipitate intradialytic symptoms. This review outlines emerging objective techniques to enhance the assessment of fluid overload in children on dialysis and outlines evidence for current management strategies to address this clinical problem. |
format | Online Article Text |
id | pubmed-6311194 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-63111942019-01-10 Assessment and management of fluid overload in children on dialysis Hayes, Wesley Paglialonga, Fabio Pediatr Nephrol Educational Review Dysregulation of intravascular fluid leads to chronic volume overload in children with end-stage kidney disease (ESKD). Sequelae include left ventricular hypertrophy and remodeling and impaired cardiac function. As a result, cardiovascular complications are the commonest cause of mortality in the pediatric dialysis population. The clinical need to optimize intravascular volume in children with ESKD is clear; however, its assessment and management is the most challenging aspect of the pediatric dialysis prescription. Minimizing chronic fluid overload is a key priority; however, excessive ultrafiltration is toxic to the myocardium and can precipitate intradialytic symptoms. This review outlines emerging objective techniques to enhance the assessment of fluid overload in children on dialysis and outlines evidence for current management strategies to address this clinical problem. Springer Berlin Heidelberg 2018-03-09 2019 /pmc/articles/PMC6311194/ /pubmed/29523958 http://dx.doi.org/10.1007/s00467-018-3916-4 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Educational Review Hayes, Wesley Paglialonga, Fabio Assessment and management of fluid overload in children on dialysis |
title | Assessment and management of fluid overload in children on dialysis |
title_full | Assessment and management of fluid overload in children on dialysis |
title_fullStr | Assessment and management of fluid overload in children on dialysis |
title_full_unstemmed | Assessment and management of fluid overload in children on dialysis |
title_short | Assessment and management of fluid overload in children on dialysis |
title_sort | assessment and management of fluid overload in children on dialysis |
topic | Educational Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311194/ https://www.ncbi.nlm.nih.gov/pubmed/29523958 http://dx.doi.org/10.1007/s00467-018-3916-4 |
work_keys_str_mv | AT hayeswesley assessmentandmanagementoffluidoverloadinchildrenondialysis AT paglialongafabio assessmentandmanagementoffluidoverloadinchildrenondialysis |