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Pancreatic Head Carcinoma-Implications and Correlations in a Romanian Population

Introduction: Pancreatic cancers are often an aggressive type of malignancy, with a 5-year survival rate estimated at around 5%. The main purpose of our study was to determine whether or not tumor dimensions influence the presence of jaundice and the diameters of the CBD and Wirsung duct. Material a...

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Autores principales: FLORESCU, L.M., GHEONEA, I.A., LĂPĂDAT, A.M., FLORESCU, M.M., FLORESCU, A., CIUREA, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical University Publishing House Craiova 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311222/
https://www.ncbi.nlm.nih.gov/pubmed/30647942
http://dx.doi.org/10.12865/CHSJ.44.03.05
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author FLORESCU, L.M.
GHEONEA, I.A.
LĂPĂDAT, A.M.
FLORESCU, M.M.
FLORESCU, A.
CIUREA, T.
author_facet FLORESCU, L.M.
GHEONEA, I.A.
LĂPĂDAT, A.M.
FLORESCU, M.M.
FLORESCU, A.
CIUREA, T.
author_sort FLORESCU, L.M.
collection PubMed
description Introduction: Pancreatic cancers are often an aggressive type of malignancy, with a 5-year survival rate estimated at around 5%. The main purpose of our study was to determine whether or not tumor dimensions influence the presence of jaundice and the diameters of the CBD and Wirsung duct. Material and methods: The study group included 32 patients (19 males, 13 females) diagnosed with various histological types of pancreatic head cancers who were hospitalized in the Surgery Department of the County Clinical Emergency Hospital of Craiova during 2016-2018. All 32 patients underwent an initial abdominal ultrasonography (US), followed by an abdominal computed tomography (CT) scan and an abdominal magnetic resonance imaging (MRI) with magnetic resonance cholangiopancreatography (MRCP) sequences. Results: Based on tumor dimensions, 19 (59.38%) were equal to or larger than 30mm, while 13 (40.62%) were smaller than 30mm. The average age of male patients was 65.15 years, while the average age of female patients was 60.07 years. Tumor dimensions ranged between 22mm and 52mm (33.53mm on average). Furthermore, the diameter of the CBD ranged from 5mm to 20mm (13.40mm on average), while the diameter of the Wirsung duct ranged from 3mm to 12mm (5.75 mm on average). Conclusion: In conclusion, our study reached its’ initial purpose and revealed a significant association between the tumor dimensions and the diameter of the Wirsung duct and also between the diameter of the CBD and the presence of jaundice.
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spelling pubmed-63112222019-01-15 Pancreatic Head Carcinoma-Implications and Correlations in a Romanian Population FLORESCU, L.M. GHEONEA, I.A. LĂPĂDAT, A.M. FLORESCU, M.M. FLORESCU, A. CIUREA, T. Curr Health Sci J Original Paper Introduction: Pancreatic cancers are often an aggressive type of malignancy, with a 5-year survival rate estimated at around 5%. The main purpose of our study was to determine whether or not tumor dimensions influence the presence of jaundice and the diameters of the CBD and Wirsung duct. Material and methods: The study group included 32 patients (19 males, 13 females) diagnosed with various histological types of pancreatic head cancers who were hospitalized in the Surgery Department of the County Clinical Emergency Hospital of Craiova during 2016-2018. All 32 patients underwent an initial abdominal ultrasonography (US), followed by an abdominal computed tomography (CT) scan and an abdominal magnetic resonance imaging (MRI) with magnetic resonance cholangiopancreatography (MRCP) sequences. Results: Based on tumor dimensions, 19 (59.38%) were equal to or larger than 30mm, while 13 (40.62%) were smaller than 30mm. The average age of male patients was 65.15 years, while the average age of female patients was 60.07 years. Tumor dimensions ranged between 22mm and 52mm (33.53mm on average). Furthermore, the diameter of the CBD ranged from 5mm to 20mm (13.40mm on average), while the diameter of the Wirsung duct ranged from 3mm to 12mm (5.75 mm on average). Conclusion: In conclusion, our study reached its’ initial purpose and revealed a significant association between the tumor dimensions and the diameter of the Wirsung duct and also between the diameter of the CBD and the presence of jaundice. Medical University Publishing House Craiova 2018 2018-07-15 /pmc/articles/PMC6311222/ /pubmed/30647942 http://dx.doi.org/10.12865/CHSJ.44.03.05 Text en Copyright © 2018, Medical University Publishing House Craiova http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited.
spellingShingle Original Paper
FLORESCU, L.M.
GHEONEA, I.A.
LĂPĂDAT, A.M.
FLORESCU, M.M.
FLORESCU, A.
CIUREA, T.
Pancreatic Head Carcinoma-Implications and Correlations in a Romanian Population
title Pancreatic Head Carcinoma-Implications and Correlations in a Romanian Population
title_full Pancreatic Head Carcinoma-Implications and Correlations in a Romanian Population
title_fullStr Pancreatic Head Carcinoma-Implications and Correlations in a Romanian Population
title_full_unstemmed Pancreatic Head Carcinoma-Implications and Correlations in a Romanian Population
title_short Pancreatic Head Carcinoma-Implications and Correlations in a Romanian Population
title_sort pancreatic head carcinoma-implications and correlations in a romanian population
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311222/
https://www.ncbi.nlm.nih.gov/pubmed/30647942
http://dx.doi.org/10.12865/CHSJ.44.03.05
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