Cargando…

Safety and efficacy of twice daily administration of KPI-121 1% for ocular inflammation and pain following cataract surgery

PURPOSE: KPI-121 is a nanoparticle suspension of loteprednol etabonate with improved ocular pharmacokinetics compared with marketed formulations. The efficacy and safety of KPI-121 1% ophthalmic suspension (INVELTYS™) dosed twice daily (BID) were evaluated in participants who had undergone cataract...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Terry, Sall, Kenneth, Holland, Edward J, Brazzell, R Kim, Coultas, Susan, Gupta, Preeya K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311334/ https://www.ncbi.nlm.nih.gov/pubmed/30643381 http://dx.doi.org/10.2147/OPTH.S185800

Ejemplares similares

The role of KPI-121 0.25% in the treatment of dry eye disease: penetrating the mucus barrier to treat periodic flares
por: Gupta, Preeya K., et al.
Publicado: (2021)

Update on twice-daily bromfenac sodium sesquihydrate to treat postoperative ocular inflammation following cataract extraction
por: Carreño, Ester, et al.
Publicado: (2012)

Key Performance Indicators (KPI)
por: Marr, Bernard
Publicado: (2012)

Ocular surface optimization before cataract surgery
por: Venkateswaran, Nandini, et al.
Publicado: (2022)

A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of 2 and 4 Weeks of Twice-Daily Ocular Trabodenoson in Adults with Ocular Hypertension or Primary Open-Angle Glaucoma
por: Myers, Jonathan S., et al.
Publicado: (2016)

Study of Xic -> pKpi reconstruction with the ALICE experiment
por: Joerg, Florian
Publicado: (2015)

Key Performance Indicators (KPI): Developing, Implementing, and Using Winning KPIs
por: Parmenter, David
Publicado: (2010)

Comparison of once-daily versus twice-daily combination of Ropinirole prolonged release in Parkinson’s disease
por: Yun, Ji Young, et al.
Publicado: (2013)

Twice-Daily versus Once-Daily Pramipexole Extended Release Dosage Regimens in Parkinson's Disease
por: Yun, Ji Young, et al.
Publicado: (2017)

Ocular pharmacokinetics and tolerability of bimatoprost ophthalmic solutions administered once or twice daily in rabbits, and clinical dosing implications
por: Shen, Jie, et al.
Publicado: (2017)

Magnesium Hydroxide Nanoparticles Improve the Ocular Hypotensive Effect of Twice Daily Topical Timolol Maleate in Healthy Dogs
por: Kita, Mizuki, et al.
Publicado: (2021)

Practical guide to choosing dabigatran 150 mg twice daily or apixaban 5 mg twice daily for patients with atrial fibrillation
por: Kobayashi, Zen, et al.
Publicado: (2019)

Impact of Preoperative Video Education for Cataract Surgery on Patient Learning Outcomes
por: Wisely, C Ellis, et al.
Publicado: (2020)

Compliance with Once-Daily versus Twice or Thrice-Daily Administration of Antibiotic Regimens: A Meta-Analysis of Randomized Controlled Trials
por: Falagas, Matthew E., et al.
Publicado: (2015)

Study of Kpi, K+K- and Kp production in DIRAC using time-of-flight measurements
por: Adeva, B, et al.
Publicado: (2007)

Diffractive dissociation of p --> pK0Kpi at $\sqrt{s}$ = 63 GeV
por: Chauvat, P, et al.
Publicado: (1982)

A KPI-Based Probabilistic Soft Sensor Development Approach that Maximizes the Coefficient of Determination
por: Zhang, Yue, et al.
Publicado: (2018)

Assessment of pharmacokinetics, safety, and tolerability following twice‐daily administration of molnupiravir for 10 days in healthy participants
por: Iwamoto, Marian, et al.
Publicado: (2023)

Ocular pharmacokinetics and tolerability of bimatoprost ophthalmic solutions administered once or twice daily in rabbits, and clinical dosing implications [Corrigendum]
Publicado: (2018)

Once– versus twice–daily tacrolimus: are the formulations equivalent?
por: Ciszek, Michał
Publicado: (2013)

DA-LSTM-VAE: Dual-Stage Attention-Based LSTM-VAE for KPI Anomaly Detection
por: Zhao, Yun, et al.
Publicado: (2022)

A randomized trial of once daily versus twice daily dosing of oral iron in CKD
por: Sood, Vivek, et al.
Publicado: (2023)

Comparison of once daily versus twice daily olmesartan in patients with chronic kidney disease
por: Sakai, Yukinao, et al.
Publicado: (2013)

Twice-Daily Application of HIV Microbicides Alters the Vaginal Microbiota
por: Ravel, Jacques, et al.
Publicado: (2012)

Twice Daily Prazosin and Valproic Acid in the Treatment of Flashbacks in PTSD
por: Fisher, Kristy A., et al.
Publicado: (2022)

Context is key: normalization as a novel approach to sport specific preprocessing of KPI’s for match analysis in soccer
por: Phatak, Ashwin A., et al.
Publicado: (2022)

KPI5 Is Involved in the Regulation of the Expression of Antibacterial Peptide Genes and Hemolymph Melanization in the Silkworm, Bombyx mori
por: Heng, Jingya, et al.
Publicado: (2022)

QI: Improving Physical Healthcare Recording in a Mental Health Service for Homeless People – Working With KPI's
por: Hall, Hugh, et al.
Publicado: (2022)

Management of ocular inflammation and pain following cataract surgery: focus on bromfenac ophthalmic solution
por: Cho, Hyung, et al.
Publicado: (2009)

Bioavailability of oxycodone after administration of a new prolonged-release once-daily tablet formulation in healthy subjects, in comparison to an established twice-daily tablet
por: Scheidel, Bernhard, et al.
Publicado: (2017)

Dexamethasone 0.4mg Sustained-Release Intracanalicular Insert in the Management of Ocular Inflammation and Pain Following Ophthalmic Surgery: Design, Development and Place in Therapy
por: Brooks, Cassandra C, et al.
Publicado: (2020)

Efficacy and safety of a switch from twice-daily tacrolimus to once-daily generic tacrolimus in stable liver transplant patients
por: Kim, Jong Man, et al.
Publicado: (2021)

Fluticasone furoate: once-daily evening treatment versus twice-daily treatment in moderate asthma
por: Woodcock, Ashley, et al.
Publicado: (2011)

Effects of Converting Tacrolimus Formulation from Twice-Daily to Once-Daily in Liver Transplantation Recipients
por: Thorat, Ashok, et al.
Publicado: (2014)

Twice-daily versus once-daily lisinopril and losartan for hypertension: Real-world effectiveness and safety
por: Derington, Catherine G., et al.
Publicado: (2020)

Efficacy and safety of once daily tacrolimus compared to twice daily tacrolimus after liver transplantation
por: Bzeizi, Khalid Ibrahim, et al.
Publicado: (2021)

Difluprednate ophthalmic emulsion 0.05% (Durezol(®)) administered two times daily for managing ocular inflammation and pain following cataract surgery
por: Smith, Stephen, et al.
Publicado: (2010)

RIVAroxaban TWICE daily for lysis of thrombus in the left atrial appendage in patients with non-valvular atrial fibrillation: the RIVA-TWICE study
por: Piotrowski, Roman, et al.
Publicado: (2019)

Anterior Segment Imaging in Ocular Surface Squamous Neoplasia
por: Ong, Sally S., et al.
Publicado: (2016)

Risk Factors for the Adverse Events after Conversion from Twice-Daily to Once-Daily Tacrolimus in Stable Liver Transplantation Patients
por: Suh, Suk-Won, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_s0uinidcugd4d8l48b56b6sm7a