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Overcoming Poor Solubility of Dimenhydrinate: Development, Optimization and Evaluation of Fast Dissolving Oral Film

Purpose: To develop fast dissolving oral film to address vomiting and nausea in pediatric population. Methods: Oral films of Dimenhydrinate were prepared by solvent casting method by using hydroxypropylmethyl cellulose E5 (HPMC E5), polyethylene glycol 400 (PEG 400) and croscarmellose sodium. Solubi...

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Detalles Bibliográficos
Autores principales: Jadhav, Yuvraj Govindrao, Galgatte, Upendra Chandrakant, Chaudhari, Pravin Digambar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311638/
https://www.ncbi.nlm.nih.gov/pubmed/30607345
http://dx.doi.org/10.15171/apb.2018.081

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