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Activation of GABA(B) Receptor Suppresses Diabetic Neuropathic Pain through Toll-Like Receptor 4 Signaling Pathway in the Spinal Dorsal Horn
Diabetic neuropathic pain (DNP) is a prevalent complication in diabetes patients. Neuronal inflammation and activation of Toll-like receptor 4 (TLR4) are involved in the occurrence of DNP. However, the underlying mechanisms remain unclear. Downregulation of gamma-aminobutyric acid B (GABA(B)) recept...
Autores principales: | Liu, Peng, Yuan, Hong-Bin, Zhao, Shuang, Liu, Fei-Fei, Jiang, Yu-Qing, Guo, Yue-Xian, Wang, Xiu-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311757/ https://www.ncbi.nlm.nih.gov/pubmed/30647535 http://dx.doi.org/10.1155/2018/6016272 |
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