Effect of CXCR2 Inhibition on Behavioral Outcomes and Pathology in Rat Model of Neuromyelitis Optica

OBJECTIVE: To reduce immune-mediated damage in a rat model of neuromyelitis optica (NMO) by blocking neutrophil migration using SCH527123, a drug that inhibits CXCR2. BACKGROUND: Neuromyelitis optica is a relapsing autoimmune disease that preferentially targets the optic nerves and spinal cord leadi...

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Detalles Bibliográficos
Autores principales: Jones, Melina V., Levy, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311856/
https://www.ncbi.nlm.nih.gov/pubmed/30648122
http://dx.doi.org/10.1155/2018/9034695

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