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Discovering functional impacts of miRNAs in cancers using a causal deep learning model

BACKGROUND: Micro-RNAs (miRNAs) play a significant role in regulating gene expression under physiological and pathological conditions such as cancers. However, it remains a challenging problem to discover the target messenger RNAs (mRNAs) of a miRNA in a data driven fashion. On one hand, sequence-ba...

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Detalles Bibliográficos
Autores principales: Chen, Lujia, Lu, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311958/
https://www.ncbi.nlm.nih.gov/pubmed/30598118
http://dx.doi.org/10.1186/s12920-018-0432-0