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Discovering functional impacts of miRNAs in cancers using a causal deep learning model
BACKGROUND: Micro-RNAs (miRNAs) play a significant role in regulating gene expression under physiological and pathological conditions such as cancers. However, it remains a challenging problem to discover the target messenger RNAs (mRNAs) of a miRNA in a data driven fashion. On one hand, sequence-ba...
Autores principales: | Chen, Lujia, Lu, Xinghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311958/ https://www.ncbi.nlm.nih.gov/pubmed/30598118 http://dx.doi.org/10.1186/s12920-018-0432-0 |
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