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Clinical and molecular characteristics of MEF2D fusion-positive B-cell precursor acute lymphoblastic leukemia in childhood, including a novel translocation resulting in MEF2D-HNRNPH1 gene fusion

Fusion genes involving MEF2D have recently been identified in precursor B-cell acute lymphoblastic leukemia, mutually exclusive of the common risk stratifying genetic abnormalities, although their true incidence and associated clinical characteristics remain unknown. We identified 16 cases of acute...

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Detalles Bibliográficos
Autores principales: Ohki, Kentaro, Kiyokawa, Nobutaka, Saito, Yuya, Hirabayashi, Shinsuke, Nakabayashi, Kazuhiko, Ichikawa, Hitoshi, Momozawa, Yukihide, Okamura, Kohji, Yoshimi, Ai, Ogata-Kawata, Hiroko, Sakamoto, Hiromi, Kato, Motohiro, Fukushima, Keitaro, Hasegawa, Daisuke, Fukushima, Hiroko, Imai, Masako, Kajiwara, Ryosuke, Koike, Takashi, Komori, Isao, Matsui, Atsushi, Mori, Makiko, Moriwaki, Koichi, Noguchi, Yasushi, Park, Myoung-ja, Ueda, Takahiro, Yamamoto, Shohei, Matsuda, Koichi, Yoshida, Teruhiko, Matsumoto, Kenji, Hata, Kenichiro, Kubo, Michiaki, Matsubara, Yoichi, Takahashi, Hiroyuki, Fukushima, Takashi, Hayashi, Yasuhide, Koh, Katsuyoshi, Manabe, Atsushi, Ohara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312004/
https://www.ncbi.nlm.nih.gov/pubmed/30171027
http://dx.doi.org/10.3324/haematol.2017.186320