Cargando…
Clinical and molecular characteristics of MEF2D fusion-positive B-cell precursor acute lymphoblastic leukemia in childhood, including a novel translocation resulting in MEF2D-HNRNPH1 gene fusion
Fusion genes involving MEF2D have recently been identified in precursor B-cell acute lymphoblastic leukemia, mutually exclusive of the common risk stratifying genetic abnormalities, although their true incidence and associated clinical characteristics remain unknown. We identified 16 cases of acute...
Autores principales: | Ohki, Kentaro, Kiyokawa, Nobutaka, Saito, Yuya, Hirabayashi, Shinsuke, Nakabayashi, Kazuhiko, Ichikawa, Hitoshi, Momozawa, Yukihide, Okamura, Kohji, Yoshimi, Ai, Ogata-Kawata, Hiroko, Sakamoto, Hiromi, Kato, Motohiro, Fukushima, Keitaro, Hasegawa, Daisuke, Fukushima, Hiroko, Imai, Masako, Kajiwara, Ryosuke, Koike, Takashi, Komori, Isao, Matsui, Atsushi, Mori, Makiko, Moriwaki, Koichi, Noguchi, Yasushi, Park, Myoung-ja, Ueda, Takahiro, Yamamoto, Shohei, Matsuda, Koichi, Yoshida, Teruhiko, Matsumoto, Kenji, Hata, Kenichiro, Kubo, Michiaki, Matsubara, Yoichi, Takahashi, Hiroyuki, Fukushima, Takashi, Hayashi, Yasuhide, Koh, Katsuyoshi, Manabe, Atsushi, Ohara, Akira |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312004/ https://www.ncbi.nlm.nih.gov/pubmed/30171027 http://dx.doi.org/10.3324/haematol.2017.186320 |
Ejemplares similares
-
Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia
por: Gu, Zhaohui, et al.
Publicado: (2016) -
Functional, structural, and molecular characterizations of the leukemogenic driver MEF2D-HNRNPUL1 fusion
por: Zhang, Ming, et al.
Publicado: (2022) -
Predicted transmembrane proteins with homology to Mef(A) are not responsible for complementing mef(A) deletion in the mef(A)–msr(D) macrolide efflux system in Streptococcus pneumoniae
por: Fox, Valeria, et al.
Publicado: (2021) -
Comparative Analysis Reveals Distinct and Overlapping Functions of Mef2c and Mef2d during Cardiogenesis in Xenopus laevis
por: Guo, Yanchun, et al.
Publicado: (2014) -
Characterization of a novel MEF2D-BCL9 fusion-positive acute lymphoblastic leukemia cell line
por: van Outersterp, Inge, et al.
Publicado: (2023)