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Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells

MicroRNAs, non-coding regulators of gene expression, are likely to function as important downstream effectors of many transcription factors including MYB. Optimal levels of MYB are required for transformation/maintenance of BCR-ABL-expressing cells. We investigated whether MYB silencing modulates mi...

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Detalles Bibliográficos
Autores principales:	Spagnuolo, Manuela, Regazzo, Giulia, De Dominici, Marco, Sacconi, Andrea, Pelosi, Andrea, Korita, Etleva, Marchesi, Francesco, Pisani, Francesco, Magenta, Alessandra, Lulli, Valentina, Cordone, Iole, Mengarelli, Andrea, Strano, Sabrina, Blandino, Giovanni, Rizzo, Maria G., Calabretta, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312025/ https://www.ncbi.nlm.nih.gov/pubmed/30076175 http://dx.doi.org/10.3324/haematol.2018.191213

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