Polymorphisms in DNA repair pathway genes and ABCG2 gene in advanced colorectal cancer: correlation with tumor characteristics and clinical outcome in oxaliplatin-based chemotherapy

OBJECTIVE: Multiple factors are involved in oxaliplatin-resistant process in colorectal cancer (CRC) patients including decreased drug accumulation and enhanced capacity to repair and tolerate DNA damage. In the present study, we aimed to assess the impact of six single-nucleotide polymorphisms (SNP...

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Detalles Bibliográficos
Autores principales: Hu, Xiaoyun, Qin, Wenyan, Li, Shanqiong, He, Miao, Wang, Yilin, Guan, Shu, Zhao, Haishan, Yao, Weifan, Wei, Minjie, Liu, Mingyan, Wu, Huizhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312053/
https://www.ncbi.nlm.nih.gov/pubmed/30643454
http://dx.doi.org/10.2147/CMAR.S181922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312053/
https://www.ncbi.nlm.nih.gov/pubmed/30643454
http://dx.doi.org/10.2147/CMAR.S181922

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