Francisella induced microparticulate caspase-1/gasdermin-D activation is regulated by NLRP3 independent of Pyrin

Although the study of pathogen sensing by host defense systems continues to uncover a role for inflammasome components specific to particular pathogens, gaps remain in our knowledge. After internalization, Francisella escapes from the phagosome in mononuclear cells and is thought to be detected by i...

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Detalles Bibliográficos
Autores principales: Mitra, Srabani, Dolvin, Erin, Krishnamurthy, Karthikeyan, Wewers, Mark D., Sarkar, Anasuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312237/
https://www.ncbi.nlm.nih.gov/pubmed/30596757
http://dx.doi.org/10.1371/journal.pone.0209931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312237/
https://www.ncbi.nlm.nih.gov/pubmed/30596757
http://dx.doi.org/10.1371/journal.pone.0209931

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