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Francisella induced microparticulate caspase-1/gasdermin-D activation is regulated by NLRP3 independent of Pyrin
Although the study of pathogen sensing by host defense systems continues to uncover a role for inflammasome components specific to particular pathogens, gaps remain in our knowledge. After internalization, Francisella escapes from the phagosome in mononuclear cells and is thought to be detected by i...
Autores principales: | Mitra, Srabani, Dolvin, Erin, Krishnamurthy, Karthikeyan, Wewers, Mark D., Sarkar, Anasuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312237/ https://www.ncbi.nlm.nih.gov/pubmed/30596757 http://dx.doi.org/10.1371/journal.pone.0209931 |
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