EBV-miR-BART1-5P activates AMPK/mTOR/HIF1 pathway via a PTEN independent manner to promote glycolysis and angiogenesis in nasopharyngeal carcinoma

Abnormal metabolism and uncontrolled angiogenesis are two important characteristics of malignant tumors. The occurrence of both events involves many key molecular changes including miRNA. However, EBV encoded miRNAs are rarely mentioned as capable of regulating tumor metabolism and tumor angiogenesi...

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Detalles Bibliográficos
Autores principales: Lyu, Xiaoming, Wang, Jianguo, Guo, Xia, Wu, Gongfa, Jiao, Yang, Faleti, Oluwasijibomi Damola, Liu, Pengfei, Liu, Tielian, Long, Yufei, Chong, Tuotuo, Yang, Xu, Huang, Jing, He, Mingliang, Tsang, Chi Man, Tsao, Sai Wah, Wang, Qian, Jiang, Qiang, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312352/
https://www.ncbi.nlm.nih.gov/pubmed/30557400
http://dx.doi.org/10.1371/journal.ppat.1007484

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