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Engineering Human Epidermal Growth Receptor 2-Targeting Hepatitis B Virus Core Nanoparticles for siRNA Delivery in Vitro and in Vivo
[Image: see text] Hepatitis B virus core (HBc) particles acquire the capacity to disassemble and reassemble in a controlled manner, allowing entrapment and delivery of drugs and macromolecules to cells. HBc particles are made of 180–240 copies of 21 kDa protein monomers, assembled into 30–34 nm diam...
Autores principales: | Suffian, Izzat F. M., Wang, Julie T.-W., Faruqu, Farid N., Benitez, Julio, Nishimura, Yuya, Ogino, Chiaki, Kondo, Akihiko, Al-Jamal, Khuloud T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2018
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312360/ https://www.ncbi.nlm.nih.gov/pubmed/30613831 http://dx.doi.org/10.1021/acsanm.8b00480 |
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