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Engineering Human Epidermal Growth Receptor 2-Targeting Hepatitis B Virus Core Nanoparticles for siRNA Delivery in Vitro and in Vivo

[Image: see text] Hepatitis B virus core (HBc) particles acquire the capacity to disassemble and reassemble in a controlled manner, allowing entrapment and delivery of drugs and macromolecules to cells. HBc particles are made of 180–240 copies of 21 kDa protein monomers, assembled into 30–34 nm diam...

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Detalles Bibliográficos
Autores principales: Suffian, Izzat F. M., Wang, Julie T.-W., Faruqu, Farid N., Benitez, Julio, Nishimura, Yuya, Ogino, Chiaki, Kondo, Akihiko, Al-Jamal, Khuloud T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312360/
https://www.ncbi.nlm.nih.gov/pubmed/30613831
http://dx.doi.org/10.1021/acsanm.8b00480

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