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RAB10: an Alzheimer’s disease resilience locus and potential drug target

Alzheimer’s disease (AD) is mainly a late-onset neurodegenerative disorder. Substantial efforts have been made to solve the complex genetic architecture of AD as a means to identify therapeutic targets. Unfortunately, to date, no disease-altering therapeutics have been developed. As therapeutics are...

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Detalles Bibliográficos
Autores principales: Tavana, Justina P, Rosene, Matthew, Jensen, Nick O, Ridge, Perry G, Kauwe, John SK, Karch, Celeste M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312396/
https://www.ncbi.nlm.nih.gov/pubmed/30643396
http://dx.doi.org/10.2147/CIA.S159148