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RAB10: an Alzheimer’s disease resilience locus and potential drug target
Alzheimer’s disease (AD) is mainly a late-onset neurodegenerative disorder. Substantial efforts have been made to solve the complex genetic architecture of AD as a means to identify therapeutic targets. Unfortunately, to date, no disease-altering therapeutics have been developed. As therapeutics are...
Autores principales: | Tavana, Justina P, Rosene, Matthew, Jensen, Nick O, Ridge, Perry G, Kauwe, John SK, Karch, Celeste M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312396/ https://www.ncbi.nlm.nih.gov/pubmed/30643396 http://dx.doi.org/10.2147/CIA.S159148 |
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