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Concise Review: The Current State of Human In Vitro Cardiac Disease Modeling: A Focus on Gene Editing and Tissue Engineering

Until recently, in vivo and ex vivo experiments were the only means to determine factors and pathways involved in disease pathophysiology. After the generation of characterized human embryonic stem cell lines, human diseases could readily be studied in an extensively controllable setting. The introd...

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Detalles Bibliográficos
Autores principales: Hoes, Martijn F., Bomer, Nils, van der Meer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312446/
https://www.ncbi.nlm.nih.gov/pubmed/30302938
http://dx.doi.org/10.1002/sctm.18-0052