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Endogenous rRNA Sequence Variation Can Regulate Stress Response Gene Expression and Phenotype
Prevailing dogma holds that ribosomes are uniform in composition and function. Here, we show that nutrient limitation-induced stress in E. coli changes the relative expression of rDNA operons to alter the rRNA composition within the actively translating ribosome pool. The most upregulated operon enc...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312700/ https://www.ncbi.nlm.nih.gov/pubmed/30282032 http://dx.doi.org/10.1016/j.celrep.2018.08.093 |