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Modeling and Simulation of hGAT1: A Mechanistic Investigation of the GABA Transport Process
Human γ-Aminobutyric acid transporter 1 (hGAT1) is a Na(+)/Cl(−) dependent co-transporter that plays a key role in the inhibitory neurotransmission of GABA in the brain. Due to the lack of structural data, the exact co-transport mechanism of GABA reuptake by hGAT1 remains unclear. To examine the rol...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312766/ https://www.ncbi.nlm.nih.gov/pubmed/30619541 http://dx.doi.org/10.1016/j.csbj.2018.12.003 |