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Alsterpaullone induces apoptosis of HepG2 cells via a p38 mitogen-activated protein kinase signaling pathway

Alsterpaullone (Alp) is a small-molecule inhibitor that targets cyclin-dependent kinases to inhibit tumor cell activity. However, to the best of our knowledge, the effect of Alp on hepatoblastoma has not been investigated. Therefore, the function of Alp in apoptotic induction of hepatoblastoma cells...

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Detalles Bibliográficos
Autores principales: Yin, Peng, Zheng, Nanxin, Dong, Junfeng, Xu, Chunyang, Zhang, Xiaomei, Ding, Guoshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312958/
https://www.ncbi.nlm.nih.gov/pubmed/30655881
http://dx.doi.org/10.3892/ol.2018.9700