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Diprophylline inhibits non-small cell lung cancer A549 cell proliferation and migration, and promotes apoptosis, by downregulating PI3K signaling pathway

Diprophylline (DPL) is identified as a methylxanthine (MX) derivative. A number of MX derivatives are reported to have anti-tumor effects. However, it is not clear whether DPL has a therapeutic effect on non-small cell lung cancer (NSCLC). The aim of the present study was to investigate the effects...

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Detalles Bibliográficos
Autores principales: Zhao, Hong-Ying, Ren, Yun-Hui, Ren, Xiu-Bao, Wang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312961/
https://www.ncbi.nlm.nih.gov/pubmed/30655839
http://dx.doi.org/10.3892/ol.2018.9678