Cargando…

Diprophylline inhibits non-small cell lung cancer A549 cell proliferation and migration, and promotes apoptosis, by downregulating PI3K signaling pathway

Diprophylline (DPL) is identified as a methylxanthine (MX) derivative. A number of MX derivatives are reported to have anti-tumor effects. However, it is not clear whether DPL has a therapeutic effect on non-small cell lung cancer (NSCLC). The aim of the present study was to investigate the effects...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Hong-Ying, Ren, Yun-Hui, Ren, Xiu-Bao, Wang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312961/ https://www.ncbi.nlm.nih.gov/pubmed/30655839 http://dx.doi.org/10.3892/ol.2018.9678

Ejemplares similares

Characteristics of Diprophylline-Induced Bidirectional Modulation on Rat Jejunal Contractility
por: Liu, Fang-Fei, et al.
Publicado: (2014)

Bostrycin inhibits proliferation of human lung carcinoma A549 cells via downregulation of the PI3K/Akt pathway
por: Chen, Wei-Sheng, et al.
Publicado: (2011)

Etomidate inhibits cell proliferation and induces apoptosis in A549 non-small cell lung cancer cells via downregulating WWP2
por: Li, Deqiang, et al.
Publicado: (2021)

PTEN Inhibits Cell Proliferation, Promotes Cell Apoptosis, and Induces Cell Cycle Arrest via Downregulating the PI3K/AKT/hTERT Pathway in Lung Adenocarcinoma A549 Cells
por: Lu, Xiao-Xiao, et al.
Publicado: (2016)

The effect of tetrandrine combined with cisplatin on proliferation and apoptosis of A549/DDP cells and A549 cells
por: Ye, Ling-Yun, et al.
Publicado: (2017)

microRNA-99a is downregulated and promotes proliferation, migration and invasion in non-small cell lung cancer A549 and H1299 cells
por: CHEN, CHANGJIN, et al.
Publicado: (2015)

Downregulation of PITX2 inhibits the proliferation and migration of liver cancer cells and induces cell apoptosis
por: Tuerxun, Kebinuer, et al.
Publicado: (2021)

Downregulation of RAGE Inhibits Cell Proliferation and Induces Apoptosis via Regulation of PI3K/AKT Pathway in Cervical Squamous Cell Carcinoma
por: Li, Ruyi, et al.
Publicado: (2020)

UNBS5162 inhibits the proliferation of human A549 non‐small‐cell lung cancer cells by promoting apoptosis
por: Liu, Cuicui, et al.
Publicado: (2017)

Combined Treatment of Dendrosomal-Curcumin and Daunorubicin Synergistically Inhibit Cell Proliferation, Migration and Induce Apoptosis in A549 Lung Cancer Cells
por: Eslami, Seyed Sadegh, et al.
Publicado: (2023)

Reversine inhibits proliferation, invasion and migration and induces cell apoptosis in gastric cancer cells by downregulating TTK
por: Xia, Pengfei, et al.
Publicado: (2021)

EGCG inhibited bladder cancer T24 and 5637 cell proliferation and migration via PI3K/AKT pathway
por: Luo, Ke-Wang, et al.
Publicado: (2018)

miR-378 associated with proliferation, migration and apoptosis properties in A549 cells and targeted NPNT in COPD
por: Qian, Guoqing, et al.
Publicado: (2022)

Downregulation of DEPTOR inhibits the proliferation, migration, and survival of osteosarcoma through PI3K/Akt/mTOR pathway
por: Hu, Binwu, et al.
Publicado: (2017)

Luteolin inhibits A549 cells proliferation and migration by down-regulating androgen receptors
por: Li, Xu, et al.
Publicado: (2023)

Piperine Inhibits Cell Proliferation and Induces Apoptosis of Human Gastric Cancer Cells by Downregulating Phosphatidylinositol 3-Kinase (PI3K)/Akt Pathway
por: Chen, Hanyu, et al.
Publicado: (2020)

SCARA5 suppresses the proliferation and migration, and promotes the apoptosis of human retinoblastoma cells by inhibiting the PI3K/AKT pathway
por: Wang, Jinwei, et al.
Publicado: (2021)

Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration
por: Nie, Xiaobo, et al.
Publicado: (2019)

KLHL18 inhibits the proliferation, migration, and invasion of non-small cell lung cancer by inhibiting PI3K/PD-L1 axis activity
por: Jiang, Xizi, et al.
Publicado: (2020)

Dieckol inhibits non‐small–cell lung cancer cell proliferation and migration by regulating the PI3K/AKT signaling pathway
por: Wang, Chun‐Hong, et al.
Publicado: (2019)

Downregulation of VEGFA inhibits proliferation, promotes apoptosis, and suppresses migration and invasion of renal clear cell carcinoma
por: Zeng, Fan-Chang, et al.
Publicado: (2016)

Silencing BMP-2 expression inhibits A549 and H460 cell proliferation and migration
por: Chu, Heying, et al.
Publicado: (2014)

MicroRNA-16-1 Inhibits Tumor Cell Proliferation and Induces Apoptosis in A549 Non-Small Cell Lung Carcinoma Cells
por: Wang, Weihua, et al.
Publicado: (2016)

Downregulation of miR-34a Promotes Proliferation and Inhibits Apoptosis of Rat Osteoarthritic Cartilage Cells by Activating PI3K/Akt Pathway
por: Tao, Haitao, et al.
Publicado: (2020)

Breviscapine regulates the proliferation, migration, invasion, and apoptosis of colorectal cancer cells via the PI3K/AKT pathway
por: Niu, Pengfei, et al.
Publicado: (2023)

Inhibition of APLN suppresses cell proliferation and migration and promotes cell apoptosis in esophageal cancer cells in vitro, through activating PI3K/mTOR signaling pathway
por: Wang, Yuhan, et al.
Publicado: (2022)

Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and induces apoptosis via PI3K/AKT pathway
por: Hao, Jiaqi, et al.
Publicado: (2017)

Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway
por: Ma, Zhenling, et al.
Publicado: (2021)

Scutellarin inhibits the glioma cell proliferation by downregulating BIRC5 to promote cell apoptosis
por: Wang, Feng, et al.
Publicado: (2023)

So-Cheong-Ryong-Tang induces apoptosis through activation of the intrinsic and extrinsic apoptosis pathways, and inhibition of the PI3K/Akt signaling pathway in non-small-cell lung cancer A549 cells
por: Park, Cheol, et al.
Publicado: (2015)

Effect of taurine on cell proliferation and apoptosis human lung cancer A549 cells
por: Tu, Shuo, et al.
Publicado: (2018)

Downregulation of FHOD1 Inhibits Metastatic Potential in A549 Cells
por: Hałas-Wiśniewska, Marta, et al.
Publicado: (2021)

βcaryophyllene oxide induces apoptosis and inhibits proliferation of A549 lung cancer cells
por: Shabana, Sameh M., et al.
Publicado: (2023)

Vitexin induces apoptosis through mitochondrial pathway and PI3K/Akt/mTOR signaling in human non-small cell lung cancer A549 cells
por: Liu, Xiaoli, et al.
Publicado: (2019)

Effect of daphnoretin on the proliferation and apoptosis of A549 lung cancer cells in vitro
por: JIANG, HONG-FANG, et al.
Publicado: (2014)

Effects of maslinic acid on the proliferation and apoptosis of A549 lung cancer cells
por: BAI, XUE, et al.
Publicado: (2016)

Anlotinib inhibits the proliferation, migration and invasion, and induces apoptosis of breast cancer cells by downregulating TFAP2C
por: Fang, Fuxiao, et al.
Publicado: (2022)

Mifepristone inhibits proliferation, migration and invasion of HUUA cells and promotes its apoptosis by regulation of FAK and PI3K/AKT signaling pathway
por: Sang, Lin, et al.
Publicado: (2018)

Tepotinib suppresses proliferation, invasion, migration, and promotes apoptosis of melanoma cells via inhibiting MET and PI3K/AKT signaling pathways
por: Jing, Guifang, et al.
Publicado: (2022)

XAV939 inhibits the proliferation and migration of lung adenocarcinoma A549 cells through the WNT pathway
por: Li, Chong, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ss0vnt72jgm4lcode652422vi8