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Comprehensive MicroRNAome Analysis of the Relationship Between Alzheimer Disease and Cancer in PSEN Double-Knockout Mice
PURPOSE: Presenilins are functionally important components of γ-secretase, which cleaves a number of transmembrane proteins. Manipulations of PSEN1 and PSEN2 have been separately studied in Alzheimer disease (AD) and cancer because both involve substrates of γ-secretase. However, numerous clinical s...
Autores principales: | Ham, Suji, Kim, Tae Kyoo, Ryu, Jeewon, Kim, Yong Sik, Tang, Ya-Ping, Im, Heh-In |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Continence Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312969/ https://www.ncbi.nlm.nih.gov/pubmed/30599494 http://dx.doi.org/10.5213/inj.1836274.137 |
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