Cargando…
Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center
PURPOSE: Augmentation cystoplasty (AC) is a surgical procedure used in adults and children with refractory bladder dysfunction, including a small bladder capacity and inadequate bladder compliance, and in whom conservative and medical treatment has failed. This study was aimed to determine the long-...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Continence Society
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312970/ https://www.ncbi.nlm.nih.gov/pubmed/30599500 http://dx.doi.org/10.5213/inj.1836174.087 |
_version_ | 1783383861443428352 |
---|---|
author | Mehmood, Shahbaz Alhazmi, Hamdan Al-Shayie, Mohammed Althobity, Ahmed Alshammari, Ahmed Altaweel, Waleed Mohamed Almathami, Ahmed Vallasciani, Santiago |
author_facet | Mehmood, Shahbaz Alhazmi, Hamdan Al-Shayie, Mohammed Althobity, Ahmed Alshammari, Ahmed Altaweel, Waleed Mohamed Almathami, Ahmed Vallasciani, Santiago |
author_sort | Mehmood, Shahbaz |
collection | PubMed |
description | PURPOSE: Augmentation cystoplasty (AC) is a surgical procedure used in adults and children with refractory bladder dysfunction, including a small bladder capacity and inadequate bladder compliance, and in whom conservative and medical treatment has failed. This study was aimed to determine the long-term outcomes of AC in children. METHODS: A retrospective analysis was conducted of 42 patients (31 males; mean age, 14.2±6.2 years) who underwent AC for neurogenic and nonneurogenic bladder dysfunction, with a median 12.0±1.5 years of follow-up. All patients underwent AC using the ileum with or without continent reconstruction. Pre-AC, concurrent, and post-AC procedures and complications were analyzed. Patients who underwent ureterocystoplasty, were lost to follow-up, or had less than 10 years of follow-up were excluded. The primary outcomes were the complication and continence rates, the post-AC linear rate of height and weight gain, and renal function. The Student t-test was used to evaluate between-group differences and the paired t-test was used to evaluate longitudinal changes in measured variables. RESULTS: Renal function was stable or improved in 32 of 42 patients (76.2%), with a post-AC continence rate of 88.1%. Thirty patients (71.4%) required 72 procedures post-AC. There was no statistically significant difference in the mean percentile of height (P=0. 212) or weight (P=0.142) of patients in the pre- and post-AC periods. No cases of bladder perforation or malignancy were detected. CONCLUSIONS: We consider AC to be a safe and effective procedure that does not negatively affect future physical growth, while achieving a good rate of stable renal function. Patients need long-term follow-up to address long-term complications. |
format | Online Article Text |
id | pubmed-6312970 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Korean Continence Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-63129702019-01-09 Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center Mehmood, Shahbaz Alhazmi, Hamdan Al-Shayie, Mohammed Althobity, Ahmed Alshammari, Ahmed Altaweel, Waleed Mohamed Almathami, Ahmed Vallasciani, Santiago Int Neurourol J Original Article PURPOSE: Augmentation cystoplasty (AC) is a surgical procedure used in adults and children with refractory bladder dysfunction, including a small bladder capacity and inadequate bladder compliance, and in whom conservative and medical treatment has failed. This study was aimed to determine the long-term outcomes of AC in children. METHODS: A retrospective analysis was conducted of 42 patients (31 males; mean age, 14.2±6.2 years) who underwent AC for neurogenic and nonneurogenic bladder dysfunction, with a median 12.0±1.5 years of follow-up. All patients underwent AC using the ileum with or without continent reconstruction. Pre-AC, concurrent, and post-AC procedures and complications were analyzed. Patients who underwent ureterocystoplasty, were lost to follow-up, or had less than 10 years of follow-up were excluded. The primary outcomes were the complication and continence rates, the post-AC linear rate of height and weight gain, and renal function. The Student t-test was used to evaluate between-group differences and the paired t-test was used to evaluate longitudinal changes in measured variables. RESULTS: Renal function was stable or improved in 32 of 42 patients (76.2%), with a post-AC continence rate of 88.1%. Thirty patients (71.4%) required 72 procedures post-AC. There was no statistically significant difference in the mean percentile of height (P=0. 212) or weight (P=0.142) of patients in the pre- and post-AC periods. No cases of bladder perforation or malignancy were detected. CONCLUSIONS: We consider AC to be a safe and effective procedure that does not negatively affect future physical growth, while achieving a good rate of stable renal function. Patients need long-term follow-up to address long-term complications. Korean Continence Society 2018-12 2018-12-31 /pmc/articles/PMC6312970/ /pubmed/30599500 http://dx.doi.org/10.5213/inj.1836174.087 Text en Copyright © 2018 Korean Continence Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Mehmood, Shahbaz Alhazmi, Hamdan Al-Shayie, Mohammed Althobity, Ahmed Alshammari, Ahmed Altaweel, Waleed Mohamed Almathami, Ahmed Vallasciani, Santiago Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center |
title | Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center |
title_full | Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center |
title_fullStr | Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center |
title_full_unstemmed | Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center |
title_short | Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center |
title_sort | long-term outcomes of augmentation cystoplasty in a pediatric population with refractory bladder dysfunction: a 12-year follow-up experience at single center |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312970/ https://www.ncbi.nlm.nih.gov/pubmed/30599500 http://dx.doi.org/10.5213/inj.1836174.087 |
work_keys_str_mv | AT mehmoodshahbaz longtermoutcomesofaugmentationcystoplastyinapediatricpopulationwithrefractorybladderdysfunctiona12yearfollowupexperienceatsinglecenter AT alhazmihamdan longtermoutcomesofaugmentationcystoplastyinapediatricpopulationwithrefractorybladderdysfunctiona12yearfollowupexperienceatsinglecenter AT alshayiemohammed longtermoutcomesofaugmentationcystoplastyinapediatricpopulationwithrefractorybladderdysfunctiona12yearfollowupexperienceatsinglecenter AT althobityahmed longtermoutcomesofaugmentationcystoplastyinapediatricpopulationwithrefractorybladderdysfunctiona12yearfollowupexperienceatsinglecenter AT alshammariahmed longtermoutcomesofaugmentationcystoplastyinapediatricpopulationwithrefractorybladderdysfunctiona12yearfollowupexperienceatsinglecenter AT altaweelwaleedmohamed longtermoutcomesofaugmentationcystoplastyinapediatricpopulationwithrefractorybladderdysfunctiona12yearfollowupexperienceatsinglecenter AT almathamiahmed longtermoutcomesofaugmentationcystoplastyinapediatricpopulationwithrefractorybladderdysfunctiona12yearfollowupexperienceatsinglecenter AT vallascianisantiago longtermoutcomesofaugmentationcystoplastyinapediatricpopulationwithrefractorybladderdysfunctiona12yearfollowupexperienceatsinglecenter |