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Carvedilol suppresses malignant proliferation of mammary epithelial cells through inhibition of the ROS-mediated PI3K/AKT signaling pathway

Reactive oxygen species (ROS) cause oncogenic mutations through direct interaction with DNA. Carvedilol (CAR) exhibits antioxidative activity, and pre-clinical studies have identified that CAR may prevent malignant transformation in certain carcinogenic models. This suggests that CAR may be a potent...

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Detalles Bibliográficos
Autores principales:	Ma, Zhongbing, Liu, Xingli, Zhang, Qiang, Yu, Zhigang, Gao, Dezong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312993/ https://www.ncbi.nlm.nih.gov/pubmed/30483797 http://dx.doi.org/10.3892/or.2018.6873

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