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Serotonin and Norepinephrine Transporter Occupancy of Tramadol in Nonhuman Primate Using Positron Emission Tomography

BACKGROUND: Tramadol, a centrally acting analgesic drug, has relatively high affinity to serotonin transporter and norepinephrine transporter in addition to μ-opioid receptor. Based on this characteristic, tramadol is expected to have an antidepressant effect. METHODS: Positron emission tomography m...

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Detalles Bibliográficos
Autores principales:	Arakawa, Ryosuke, Takano, Akihiro, Halldin, Christer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313119/ https://www.ncbi.nlm.nih.gov/pubmed/30346535 http://dx.doi.org/10.1093/ijnp/pyy089

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