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Diagnostic value of ultrasound combined with magnetic resonance imaging in different stages of breast cancer

Diagnostic value of ultrasound (US) and magnetic resonance imaging (MRI) in breast cancer were investigated. One hundred and forty breast cancer patients diagnosed in Heping Hospital Affiliated to Changzhi Medical College from June 2016 to June 2018 were collected, used as breast cancer group, 80 pa...

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Autores principales: Pan, Qiaohong, Ji, Jianwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313192/
https://www.ncbi.nlm.nih.gov/pubmed/30655757
http://dx.doi.org/10.3892/ol.2018.9589
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author Pan, Qiaohong
Ji, Jianwu
author_facet Pan, Qiaohong
Ji, Jianwu
author_sort Pan, Qiaohong
collection PubMed
description Diagnostic value of ultrasound (US) and magnetic resonance imaging (MRI) in breast cancer were investigated. One hundred and forty breast cancer patients diagnosed in Heping Hospital Affiliated to Changzhi Medical College from June 2016 to June 2018 were collected, used as breast cancer group, 80 patients with benign breast tumor in the same period were the benign group. Pathological results were used to compare the diagnostic coincidence of US and MRI in breast cancer patients. The positive expression case rates of estrogen receptor and progesterone receptor were significantly higher in breast cancer group than those in benign group, but that of human epidermal growth factor receptor 2 (Her-2) was significantly lower in breast cancer group than that in benign group (all P<0.05). The sensitivity (SEN) of MRI alone and that of US combined with MRI were higher than that of US alone (P<0.05). The specificity (SPE) of MRI alone was lower than that of US alone and US combined with MRI (P<0.05). The NPV of US combined with MRI was significantly higher than that of US alone (P<0.05). The Youden index (YI) of US combined with MRI was significantly higher than that of US alone and MRI alone. In the diagnosis of N2, that of US combined with MRI was significantly higher than those of US alone and MRI alone (P<0.05). In stages of M0 and M1 among three methods, those of MRI alone and US combined with MRI were higher than that of US alone (P<0.05). US combined with MRI for the diagnosis of breast cancer has higher SEN and SPE, with better accuracy rate for the identification of each stage. Reducing the incidence of missed diagnosis and misdiagnosis that may be caused by single diagnosis and treatment, it is conducive to clinical screening and guiding clinical symptomatic treatment.
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spelling pubmed-63131922019-01-17 Diagnostic value of ultrasound combined with magnetic resonance imaging in different stages of breast cancer Pan, Qiaohong Ji, Jianwu Oncol Lett Articles Diagnostic value of ultrasound (US) and magnetic resonance imaging (MRI) in breast cancer were investigated. One hundred and forty breast cancer patients diagnosed in Heping Hospital Affiliated to Changzhi Medical College from June 2016 to June 2018 were collected, used as breast cancer group, 80 patients with benign breast tumor in the same period were the benign group. Pathological results were used to compare the diagnostic coincidence of US and MRI in breast cancer patients. The positive expression case rates of estrogen receptor and progesterone receptor were significantly higher in breast cancer group than those in benign group, but that of human epidermal growth factor receptor 2 (Her-2) was significantly lower in breast cancer group than that in benign group (all P<0.05). The sensitivity (SEN) of MRI alone and that of US combined with MRI were higher than that of US alone (P<0.05). The specificity (SPE) of MRI alone was lower than that of US alone and US combined with MRI (P<0.05). The NPV of US combined with MRI was significantly higher than that of US alone (P<0.05). The Youden index (YI) of US combined with MRI was significantly higher than that of US alone and MRI alone. In the diagnosis of N2, that of US combined with MRI was significantly higher than those of US alone and MRI alone (P<0.05). In stages of M0 and M1 among three methods, those of MRI alone and US combined with MRI were higher than that of US alone (P<0.05). US combined with MRI for the diagnosis of breast cancer has higher SEN and SPE, with better accuracy rate for the identification of each stage. Reducing the incidence of missed diagnosis and misdiagnosis that may be caused by single diagnosis and treatment, it is conducive to clinical screening and guiding clinical symptomatic treatment. D.A. Spandidos 2019-01 2018-10-17 /pmc/articles/PMC6313192/ /pubmed/30655757 http://dx.doi.org/10.3892/ol.2018.9589 Text en Copyright: © Pan et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Pan, Qiaohong
Ji, Jianwu
Diagnostic value of ultrasound combined with magnetic resonance imaging in different stages of breast cancer
title Diagnostic value of ultrasound combined with magnetic resonance imaging in different stages of breast cancer
title_full Diagnostic value of ultrasound combined with magnetic resonance imaging in different stages of breast cancer
title_fullStr Diagnostic value of ultrasound combined with magnetic resonance imaging in different stages of breast cancer
title_full_unstemmed Diagnostic value of ultrasound combined with magnetic resonance imaging in different stages of breast cancer
title_short Diagnostic value of ultrasound combined with magnetic resonance imaging in different stages of breast cancer
title_sort diagnostic value of ultrasound combined with magnetic resonance imaging in different stages of breast cancer
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313192/
https://www.ncbi.nlm.nih.gov/pubmed/30655757
http://dx.doi.org/10.3892/ol.2018.9589
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