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IQOS(TM) vs. e-Cigarette vs. Tobacco Cigarette: A Direct Comparison of Short-Term Effects after Overnight-Abstinence

Introduction: Research from Philip Morris International’s science division on its Heat-not-Burn product IQOS(TM) focused on its chemical, toxicological, clinical, and behavioral aspects. Independent research on the experiences and behavioral aspects of using IQOS(TM), and how it compares to e-cigare...

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Detalles Bibliográficos
Autores principales: Adriaens, Karolien, Van Gucht, Dinska, Baeyens, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313326/
https://www.ncbi.nlm.nih.gov/pubmed/30567400
http://dx.doi.org/10.3390/ijerph15122902
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author Adriaens, Karolien
Van Gucht, Dinska
Baeyens, Frank
author_facet Adriaens, Karolien
Van Gucht, Dinska
Baeyens, Frank
author_sort Adriaens, Karolien
collection PubMed
description Introduction: Research from Philip Morris International’s science division on its Heat-not-Burn product IQOS(TM) focused on its chemical, toxicological, clinical, and behavioral aspects. Independent research on the experiences and behavioral aspects of using IQOS(TM), and how it compares to e-cigarettes, is largely lacking. The current randomized, cross-over behavioral trial tried to bridge the latter gaps. Methods: Participants (n = 30) came to the lab on three consecutive days after being overnight smoking abstinent. During each session, participants used one of three products (cigarette, e-cigarette, or IQOS(TM)) for five minutes. Exhaled CO (eCO) measurements and questionnaires were repeatedly administered throughout the session. Results: Smoking a cigarette for five minutes resulted in a significant increase of eCO, whereas using an IQOS(TM) resulted in a small but reliable increase (0.3 ppm). Vaping did not affect eCO. Cigarette craving reduced significantly after product use, with the decline being stronger for smoking than for e-cigarettes or IQOS(TM). Withdrawal symptoms declined immediately after smoking or using IQOS(TM), and with some delay after vaping. IQOS(TM) scored higher in terms of subjective reward/satisfaction and was slightly preferred to the e-cigarette. Discussion: Short-term use of IQOS(TM) has a minimal impact on eCO, is equally effective in reducing cigarette craving and withdrawal symptoms as an e-cigarette, and is slightly preferred.
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spelling pubmed-63133262019-06-17 IQOS(TM) vs. e-Cigarette vs. Tobacco Cigarette: A Direct Comparison of Short-Term Effects after Overnight-Abstinence Adriaens, Karolien Van Gucht, Dinska Baeyens, Frank Int J Environ Res Public Health Article Introduction: Research from Philip Morris International’s science division on its Heat-not-Burn product IQOS(TM) focused on its chemical, toxicological, clinical, and behavioral aspects. Independent research on the experiences and behavioral aspects of using IQOS(TM), and how it compares to e-cigarettes, is largely lacking. The current randomized, cross-over behavioral trial tried to bridge the latter gaps. Methods: Participants (n = 30) came to the lab on three consecutive days after being overnight smoking abstinent. During each session, participants used one of three products (cigarette, e-cigarette, or IQOS(TM)) for five minutes. Exhaled CO (eCO) measurements and questionnaires were repeatedly administered throughout the session. Results: Smoking a cigarette for five minutes resulted in a significant increase of eCO, whereas using an IQOS(TM) resulted in a small but reliable increase (0.3 ppm). Vaping did not affect eCO. Cigarette craving reduced significantly after product use, with the decline being stronger for smoking than for e-cigarettes or IQOS(TM). Withdrawal symptoms declined immediately after smoking or using IQOS(TM), and with some delay after vaping. IQOS(TM) scored higher in terms of subjective reward/satisfaction and was slightly preferred to the e-cigarette. Discussion: Short-term use of IQOS(TM) has a minimal impact on eCO, is equally effective in reducing cigarette craving and withdrawal symptoms as an e-cigarette, and is slightly preferred. MDPI 2018-12-18 2018-12 /pmc/articles/PMC6313326/ /pubmed/30567400 http://dx.doi.org/10.3390/ijerph15122902 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Adriaens, Karolien
Van Gucht, Dinska
Baeyens, Frank
IQOS(TM) vs. e-Cigarette vs. Tobacco Cigarette: A Direct Comparison of Short-Term Effects after Overnight-Abstinence
title IQOS(TM) vs. e-Cigarette vs. Tobacco Cigarette: A Direct Comparison of Short-Term Effects after Overnight-Abstinence
title_full IQOS(TM) vs. e-Cigarette vs. Tobacco Cigarette: A Direct Comparison of Short-Term Effects after Overnight-Abstinence
title_fullStr IQOS(TM) vs. e-Cigarette vs. Tobacco Cigarette: A Direct Comparison of Short-Term Effects after Overnight-Abstinence
title_full_unstemmed IQOS(TM) vs. e-Cigarette vs. Tobacco Cigarette: A Direct Comparison of Short-Term Effects after Overnight-Abstinence
title_short IQOS(TM) vs. e-Cigarette vs. Tobacco Cigarette: A Direct Comparison of Short-Term Effects after Overnight-Abstinence
title_sort iqos(tm) vs. e-cigarette vs. tobacco cigarette: a direct comparison of short-term effects after overnight-abstinence
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313326/
https://www.ncbi.nlm.nih.gov/pubmed/30567400
http://dx.doi.org/10.3390/ijerph15122902
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