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Blebbistatin, a Myosin II Inhibitor, Exerts Antidepressant-Like Activity and Suppresses Detrusor Overactivity in an Animal Model of Depression Coexisting with Overactive Bladder

Overactive bladder (OAB) coexists with depression in women. Here, we assessed the effects of a 1-week treatment with blebbistatin, a myosin II inhibitor, on changes in behavior and detrusor overactivity (DO) symptoms induced by a 6-week administration of 13-cis-retinoic acid (13-cis-RA), with the ai...

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Detalles Bibliográficos
Autores principales: Wróbel, Andrzej, Doboszewska, Urszula, Rechberger, Ewa, Bańczerowska-Górska, Małgorzata, Czuczwar, Piotr, Poleszak, Ewa, Dudka, Jarosław, Wlaź, Piotr, Miotła, Paweł, Wlaźlak, Edyta, Rechberger, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313360/
https://www.ncbi.nlm.nih.gov/pubmed/30155683
http://dx.doi.org/10.1007/s12640-018-9948-5