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Modulation of the Antibiotic Activity by the Mauritia flexuosa (Buriti) Fixed Oil against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Other Multidrug-Resistant (MDR) Bacterial Strains

Mauritia flexuosa (buriti) is a typical Brazilian palm tree found in swampy regions with many plant forms. The fruit has various purposes with the pulps to the seeds being used for ice creams, sweets, creams, jellies, liqueurs, and vitamin production. A physicochemical characterization of the fixed...

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Autores principales: Faustino Pereira, Yara, do Socorro Costa, Maria, Relison Tintino, Saulo, Esmeraldo Rocha, Janaína, Fernandes Galvão Rodrigues, Fábio, de Sá Barreto Feitosa, Maria Karine, de Menezes, Irwin Rose Alencar, Douglas Melo Coutinho, Henrique, da Costa, José Galberto Martins, de Sousa, Erlânio Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313460/
https://www.ncbi.nlm.nih.gov/pubmed/30544654
http://dx.doi.org/10.3390/pathogens7040098
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author Faustino Pereira, Yara
do Socorro Costa, Maria
Relison Tintino, Saulo
Esmeraldo Rocha, Janaína
Fernandes Galvão Rodrigues, Fábio
de Sá Barreto Feitosa, Maria Karine
de Menezes, Irwin Rose Alencar
Douglas Melo Coutinho, Henrique
da Costa, José Galberto Martins
de Sousa, Erlânio Oliveira
author_facet Faustino Pereira, Yara
do Socorro Costa, Maria
Relison Tintino, Saulo
Esmeraldo Rocha, Janaína
Fernandes Galvão Rodrigues, Fábio
de Sá Barreto Feitosa, Maria Karine
de Menezes, Irwin Rose Alencar
Douglas Melo Coutinho, Henrique
da Costa, José Galberto Martins
de Sousa, Erlânio Oliveira
author_sort Faustino Pereira, Yara
collection PubMed
description Mauritia flexuosa (buriti) is a typical Brazilian palm tree found in swampy regions with many plant forms. The fruit has various purposes with the pulps to the seeds being used for ice creams, sweets, creams, jellies, liqueurs, and vitamin production. A physicochemical characterization of the fixed pulp oil and its antibacterial and aminoglycoside antibiotic modifying activity against Gram-positive and Gram-negative multiresistant bacterial strains were performed using broth microdilution assays. Physical properties, such as moisture, pH, acidity, peroxide index, relative density, and refractive index, indicated oil stability and chemical quality. In the GC/MS chemical composition analysis, a high content of unsaturated fatty acids (89.81%) in relation to saturated fatty acids (10.19%) was observed. Oleic acid (89.81%) was the main fatty acid identified. In the antibacterial test, the fixed oil obtained the Minimum Inhibitory Concentration (MIC) ≥ 1024 μg/mL for all standard and multiresistant bacterial strains. The synergic effect of fixed pulp oil combined was observed only in Staphylococcus aureus SA–10, with an MIC reduction of the gentamicin and amikacin by 40.00% and 60.55%, respectively. The data indicates the M. flexuosa fixed oil as a valuable source of oleic acid and modulator of aminoglycoside activity.
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spelling pubmed-63134602019-01-07 Modulation of the Antibiotic Activity by the Mauritia flexuosa (Buriti) Fixed Oil against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Other Multidrug-Resistant (MDR) Bacterial Strains Faustino Pereira, Yara do Socorro Costa, Maria Relison Tintino, Saulo Esmeraldo Rocha, Janaína Fernandes Galvão Rodrigues, Fábio de Sá Barreto Feitosa, Maria Karine de Menezes, Irwin Rose Alencar Douglas Melo Coutinho, Henrique da Costa, José Galberto Martins de Sousa, Erlânio Oliveira Pathogens Article Mauritia flexuosa (buriti) is a typical Brazilian palm tree found in swampy regions with many plant forms. The fruit has various purposes with the pulps to the seeds being used for ice creams, sweets, creams, jellies, liqueurs, and vitamin production. A physicochemical characterization of the fixed pulp oil and its antibacterial and aminoglycoside antibiotic modifying activity against Gram-positive and Gram-negative multiresistant bacterial strains were performed using broth microdilution assays. Physical properties, such as moisture, pH, acidity, peroxide index, relative density, and refractive index, indicated oil stability and chemical quality. In the GC/MS chemical composition analysis, a high content of unsaturated fatty acids (89.81%) in relation to saturated fatty acids (10.19%) was observed. Oleic acid (89.81%) was the main fatty acid identified. In the antibacterial test, the fixed oil obtained the Minimum Inhibitory Concentration (MIC) ≥ 1024 μg/mL for all standard and multiresistant bacterial strains. The synergic effect of fixed pulp oil combined was observed only in Staphylococcus aureus SA–10, with an MIC reduction of the gentamicin and amikacin by 40.00% and 60.55%, respectively. The data indicates the M. flexuosa fixed oil as a valuable source of oleic acid and modulator of aminoglycoside activity. MDPI 2018-12-10 /pmc/articles/PMC6313460/ /pubmed/30544654 http://dx.doi.org/10.3390/pathogens7040098 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Faustino Pereira, Yara
do Socorro Costa, Maria
Relison Tintino, Saulo
Esmeraldo Rocha, Janaína
Fernandes Galvão Rodrigues, Fábio
de Sá Barreto Feitosa, Maria Karine
de Menezes, Irwin Rose Alencar
Douglas Melo Coutinho, Henrique
da Costa, José Galberto Martins
de Sousa, Erlânio Oliveira
Modulation of the Antibiotic Activity by the Mauritia flexuosa (Buriti) Fixed Oil against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Other Multidrug-Resistant (MDR) Bacterial Strains
title Modulation of the Antibiotic Activity by the Mauritia flexuosa (Buriti) Fixed Oil against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Other Multidrug-Resistant (MDR) Bacterial Strains
title_full Modulation of the Antibiotic Activity by the Mauritia flexuosa (Buriti) Fixed Oil against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Other Multidrug-Resistant (MDR) Bacterial Strains
title_fullStr Modulation of the Antibiotic Activity by the Mauritia flexuosa (Buriti) Fixed Oil against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Other Multidrug-Resistant (MDR) Bacterial Strains
title_full_unstemmed Modulation of the Antibiotic Activity by the Mauritia flexuosa (Buriti) Fixed Oil against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Other Multidrug-Resistant (MDR) Bacterial Strains
title_short Modulation of the Antibiotic Activity by the Mauritia flexuosa (Buriti) Fixed Oil against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Other Multidrug-Resistant (MDR) Bacterial Strains
title_sort modulation of the antibiotic activity by the mauritia flexuosa (buriti) fixed oil against methicillin-resistant staphylococcus aureus (mrsa) and other multidrug-resistant (mdr) bacterial strains
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313460/
https://www.ncbi.nlm.nih.gov/pubmed/30544654
http://dx.doi.org/10.3390/pathogens7040098
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