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ST-Elevation Myocardial Infarction in Coronary Ectasia: A Case Report

Coronary artery ectasia (CAE) is localized or diffuse dilatation of the coronary artery lumen exceeding the diameter of adjacent healthy reference segments by 1.5 times. It is a rare phenomenon and incidence ranges from 1 to 5% in patients undergoing angiography. We report a case of a 58-year-old ma...

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Autores principales: Choi, Hye Ji (Sally), Luong, Christina, Fung, Anthony, Tsang, Teresa S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313525/
https://www.ncbi.nlm.nih.gov/pubmed/30453473
http://dx.doi.org/10.3390/diseases6040104
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author Choi, Hye Ji (Sally)
Luong, Christina
Fung, Anthony
Tsang, Teresa S. M.
author_facet Choi, Hye Ji (Sally)
Luong, Christina
Fung, Anthony
Tsang, Teresa S. M.
author_sort Choi, Hye Ji (Sally)
collection PubMed
description Coronary artery ectasia (CAE) is localized or diffuse dilatation of the coronary artery lumen exceeding the diameter of adjacent healthy reference segments by 1.5 times. It is a rare phenomenon and incidence ranges from 1 to 5% in patients undergoing angiography. We report a case of a 58-year-old man with atherosclerotic CAE who experienced ST-elevation myocardial infarction (STEMI) despite prophylactic antiplatelet therapy. He was successfully treated with IV eptifibatide and aspiration thrombectomy. We reviewed the literature of CAE presentation, etiology and treatment and discussed the most appropriate antithrombotic therapy to prevent STEMIs in patients with CAE. While the current literature appears to favour prophylactic antiplatelet and anticoagulant in these patients, more studies are needed to determine the optimal form and duration of antithrombotic therapy. Currently, there is no gold standard treatment for CAE and further prospective and randomized-controlled studies are needed to guide recommendations.
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spelling pubmed-63135252019-01-04 ST-Elevation Myocardial Infarction in Coronary Ectasia: A Case Report Choi, Hye Ji (Sally) Luong, Christina Fung, Anthony Tsang, Teresa S. M. Diseases Case Report Coronary artery ectasia (CAE) is localized or diffuse dilatation of the coronary artery lumen exceeding the diameter of adjacent healthy reference segments by 1.5 times. It is a rare phenomenon and incidence ranges from 1 to 5% in patients undergoing angiography. We report a case of a 58-year-old man with atherosclerotic CAE who experienced ST-elevation myocardial infarction (STEMI) despite prophylactic antiplatelet therapy. He was successfully treated with IV eptifibatide and aspiration thrombectomy. We reviewed the literature of CAE presentation, etiology and treatment and discussed the most appropriate antithrombotic therapy to prevent STEMIs in patients with CAE. While the current literature appears to favour prophylactic antiplatelet and anticoagulant in these patients, more studies are needed to determine the optimal form and duration of antithrombotic therapy. Currently, there is no gold standard treatment for CAE and further prospective and randomized-controlled studies are needed to guide recommendations. MDPI 2018-11-16 /pmc/articles/PMC6313525/ /pubmed/30453473 http://dx.doi.org/10.3390/diseases6040104 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Choi, Hye Ji (Sally)
Luong, Christina
Fung, Anthony
Tsang, Teresa S. M.
ST-Elevation Myocardial Infarction in Coronary Ectasia: A Case Report
title ST-Elevation Myocardial Infarction in Coronary Ectasia: A Case Report
title_full ST-Elevation Myocardial Infarction in Coronary Ectasia: A Case Report
title_fullStr ST-Elevation Myocardial Infarction in Coronary Ectasia: A Case Report
title_full_unstemmed ST-Elevation Myocardial Infarction in Coronary Ectasia: A Case Report
title_short ST-Elevation Myocardial Infarction in Coronary Ectasia: A Case Report
title_sort st-elevation myocardial infarction in coronary ectasia: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313525/
https://www.ncbi.nlm.nih.gov/pubmed/30453473
http://dx.doi.org/10.3390/diseases6040104
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