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Association between Diabetic Retinopathy and Chronic Periodontitis—A Cross-Sectional Study

Periodontal disease (PD), a chronic inflammatory condition characterized by destruction of the supporting tissues of the teeth, increases the risk of complications in diabetics. Diabetic retinopathy (DR) is a microvascular complication of prolonged hyperglycaemia. There appears to be a similarity in...

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Autores principales: H. R., Veena, Natesh, Sribhargava, Patil, Sudhir R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313732/
https://www.ncbi.nlm.nih.gov/pubmed/30477167
http://dx.doi.org/10.3390/medsci6040104
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author H. R., Veena
Natesh, Sribhargava
Patil, Sudhir R.
author_facet H. R., Veena
Natesh, Sribhargava
Patil, Sudhir R.
author_sort H. R., Veena
collection PubMed
description Periodontal disease (PD), a chronic inflammatory condition characterized by destruction of the supporting tissues of the teeth, increases the risk of complications in diabetics. Diabetic retinopathy (DR) is a microvascular complication of prolonged hyperglycaemia. There appears to be a similarity in the pathogenesis of DR and PD. Hence, this study aimed to investigate the association, if any, between DR and PD, correlate the severity of DR with the severity of PD, and investigate the association between glycated haemoglobin (HbA1c), serum creatinine and periodontal variables. The periodontal status of 200 adult diabetic patients in the age group of 30–65 years with varying severity of DR was assessed. Evaluation of the severity of PD was assessed by recording clinical parameters. Haematological investigations including glycated haemoglobin (HbA1c) and serum creatinine were estimated before the initiation of treatment for DR. A statistically significant association between the mean duration of diabetes mellitus (DM) and the severity of DR and PD was found. The severity of PD was directly correlated with the severity of DR. There was a significant association between the levels of HbA1c and serum creatinine and severity of DR and PD. There could be a plausible relationship between DR and PD. Further prospective studies on a larger population with longer follow-ups are required to ascertain whether PD and its severity directly affect the progression and severity of DR.
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spelling pubmed-63137322019-01-04 Association between Diabetic Retinopathy and Chronic Periodontitis—A Cross-Sectional Study H. R., Veena Natesh, Sribhargava Patil, Sudhir R. Med Sci (Basel) Article Periodontal disease (PD), a chronic inflammatory condition characterized by destruction of the supporting tissues of the teeth, increases the risk of complications in diabetics. Diabetic retinopathy (DR) is a microvascular complication of prolonged hyperglycaemia. There appears to be a similarity in the pathogenesis of DR and PD. Hence, this study aimed to investigate the association, if any, between DR and PD, correlate the severity of DR with the severity of PD, and investigate the association between glycated haemoglobin (HbA1c), serum creatinine and periodontal variables. The periodontal status of 200 adult diabetic patients in the age group of 30–65 years with varying severity of DR was assessed. Evaluation of the severity of PD was assessed by recording clinical parameters. Haematological investigations including glycated haemoglobin (HbA1c) and serum creatinine were estimated before the initiation of treatment for DR. A statistically significant association between the mean duration of diabetes mellitus (DM) and the severity of DR and PD was found. The severity of PD was directly correlated with the severity of DR. There was a significant association between the levels of HbA1c and serum creatinine and severity of DR and PD. There could be a plausible relationship between DR and PD. Further prospective studies on a larger population with longer follow-ups are required to ascertain whether PD and its severity directly affect the progression and severity of DR. MDPI 2018-11-23 /pmc/articles/PMC6313732/ /pubmed/30477167 http://dx.doi.org/10.3390/medsci6040104 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
H. R., Veena
Natesh, Sribhargava
Patil, Sudhir R.
Association between Diabetic Retinopathy and Chronic Periodontitis—A Cross-Sectional Study
title Association between Diabetic Retinopathy and Chronic Periodontitis—A Cross-Sectional Study
title_full Association between Diabetic Retinopathy and Chronic Periodontitis—A Cross-Sectional Study
title_fullStr Association between Diabetic Retinopathy and Chronic Periodontitis—A Cross-Sectional Study
title_full_unstemmed Association between Diabetic Retinopathy and Chronic Periodontitis—A Cross-Sectional Study
title_short Association between Diabetic Retinopathy and Chronic Periodontitis—A Cross-Sectional Study
title_sort association between diabetic retinopathy and chronic periodontitis—a cross-sectional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313732/
https://www.ncbi.nlm.nih.gov/pubmed/30477167
http://dx.doi.org/10.3390/medsci6040104
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