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Corneal keratin aggresome (CKAGG) formation and clearance by proteasome activation

PURPOSE: To understand the mechanism of corneal keratin expression and clearance in corneal epithelium with Limbal Stem Cell Deficiency (LSCD). The hypothesis is that LSCD-induced proteasome dysfunction is a contributing factor to keratin aggregation, causing corneal keratin aggresome (CKAGG) format...

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Detalles Bibliográficos
Autores principales: Bardag-Gorce, Fawzia, Makalinao, Andrew, Meepe, Imara, Hoft, Richard H., Cortez, Daileen, Oliva, Joan, Laporte, Amanda, Stark, Jeremy, Gorce, Amber, Di Lorenzo, Michael, French, Samuel W., Lungo, William, Niihara, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313837/
https://www.ncbi.nlm.nih.gov/pubmed/30619956
http://dx.doi.org/10.1016/j.heliyon.2018.e01012

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